Respiration in Living Things Explained (Part 1) — Aerobic, Anaerobic & Amoeba/Amphibians (JAMB/WAEC)
Respiration is the biological process by which living organisms release energy stored in food, and it occurs in two main forms depending on whether oxygen is available. This is Part 1 of our Respiration series, covering aerobic and anaerobic respiration, along with how respiration works in simpler organisms like the amoeba and in amphibians.
This topic is a regular feature in JAMB and WAEC Biology, since it connects directly to cell biology, energy flow, and organism-specific adaptations. This lesson breaks each part down clearly.
Quick takeaways
- Respiration is the process by which living organisms break down food to release energy, occurring inside the mitochondria of cells.
- Aerobic respiration requires oxygen and releases a large amount of energy, producing carbon dioxide and water as byproducts.
- Anaerobic respiration occurs without oxygen and releases much less energy, producing different byproducts depending on the organism (e.g., lactic acid in humans, ethanol and carbon dioxide in yeast).
- The amoeba, a simple single-celled organism, respires directly through its cell membrane via diffusion, without specialized respiratory organs.
- Amphibians have a unique respiratory adaptation, being able to respire through their skin (cutaneous respiration) in addition to lungs, especially useful for their semi-aquatic lifestyle.
What is respiration?
Respiration is the biological process by which living organisms break down food molecules, primarily glucose, to release energy that the organism’s cells can use for their activities. This process occurs inside the mitochondria of cells, which is why the mitochondria is often referred to as the “powerhouse of the cell.” Respiration should not be confused with breathing (the physical act of inhaling and exhaling air) — breathing is simply how many organisms obtain the oxygen needed for one type of respiration.
What is aerobic respiration?
Aerobic respiration is the process of releasing energy from food using oxygen, producing carbon dioxide and water as byproducts, and it releases a much larger amount of energy compared to anaerobic respiration. It can be summarized by the equation:
Glucose + Oxygen → Carbon dioxide + Water + Energy
Aerobic respiration is the primary energy-releasing process in most complex organisms, including humans, since it’s far more efficient at extracting energy from food than the anaerobic alternative.
What is anaerobic respiration?
Anaerobic respiration is the process of releasing energy from food without using oxygen, and it produces significantly less energy than aerobic respiration since the food molecules are only partially broken down. The specific byproducts depend on the organism:
- In humans and animals — anaerobic respiration produces lactic acid, which can build up in muscles during intense exercise when oxygen supply can’t keep up with demand
- In yeast and some microorganisms — anaerobic respiration (fermentation) produces ethanol and carbon dioxide
How does an amoeba respire?
An amoeba is a simple, single-celled organism without specialized respiratory organs, so it respires through diffusion directly across its cell membrane. Oxygen diffuses into the cell from the surrounding water, and carbon dioxide diffuses out, driven by the natural difference in concentration between the inside and outside of the cell. This works efficiently for the amoeba specifically because its small size gives it a large surface-area-to-volume ratio, allowing gases to diffuse quickly enough to meet its needs without any specialized structures.
How do amphibians respire?
Amphibians have a distinctive respiratory adaptation suited to their semi-aquatic lifestyle, using multiple methods depending on their life stage and environment:
- Gills — used by amphibian larvae (such as tadpoles) while living in water
- Lungs — developed in adult amphibians for breathing air on land
- Cutaneous (skin) respiration — gas exchange occurring directly through the moist skin, supplementing lung respiration, especially useful while underwater or in humid environments
This combination allows amphibians to respire effectively both in water and on land, reflecting their evolutionary position between fully aquatic and fully terrestrial organisms.
Common mistakes students make with this topic
- Confusing respiration (a cellular, chemical process) with breathing (the physical movement of air in and out of the lungs)
- Forgetting that anaerobic respiration produces different byproducts in different organisms (lactic acid in animals vs ethanol and carbon dioxide in yeast)
- Assuming the amoeba has specialized respiratory structures, when it actually respires simply through diffusion across its cell membrane
- Overlooking cutaneous (skin) respiration as a distinct, testable method used by amphibians alongside lungs and gills
Frequently asked questions
Q: What is the difference between aerobic and anaerobic respiration? Aerobic respiration uses oxygen and releases a large amount of energy, producing carbon dioxide and water, while anaerobic respiration occurs without oxygen and releases much less energy, producing byproducts like lactic acid (in animals) or ethanol and carbon dioxide (in yeast).
Q: How does an amoeba obtain oxygen for respiration? An amoeba obtains oxygen through diffusion directly across its cell membrane, since it lacks specialized respiratory organs, relying on its small size and large surface-area-to-volume ratio for this to work efficiently.
Q: What is cutaneous respiration? Cutaneous respiration is gas exchange occurring directly through an organism’s skin, and it’s a key adaptation used by amphibians alongside lungs and gills.
Q: Why does anaerobic respiration release less energy than aerobic respiration? Because anaerobic respiration only partially breaks down food molecules without the use of oxygen, whereas aerobic respiration fully breaks down food molecules using oxygen, extracting significantly more energy in the process.
Want to see how respiration connects to energy loss in ecosystems? Read our Energy Flow lesson → or revisit Cell Biology Part 1 → for a refresher on the mitochondria’s role.
This is one topic from our full WAEC & JAMB Biology course — see everything covered →






